BDBM50306714 CHEMBL601873::Isopropyl 1,1-Dimethyl-3-[4-(3-morpholin-4-ylpropoxy)benzoyl]-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(OCCCN2CCOCC2)cc1

InChI Key InChIKey=CCNIWPQOOWKWHQ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306714   

TargetBile acid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(Isopropyl 1,1-Dimethyl-3-[4-(3-morpholin-4-ylpropo...)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBile acid receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(Isopropyl 1,1-Dimethyl-3-[4-(3-morpholin-4-ylpropo...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50306714(Isopropyl 1,1-Dimethyl-3-[4-(3-morpholin-4-ylpropo...)
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed