BDBM50306685 CHEMBL602470::rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylic acid

SMILES CC(Oc1ccc2ncc(\C=C\C(O)=O)cc2c1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=OTVUYUULIVACAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306685   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306685(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306685(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306685(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed