BDBM50306681 (S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinoline::CHEMBL598523

SMILES C[C@H](Oc1ccc2ncccc2c1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=DORFEDMRVQLEQT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50306681   

TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 453nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed