BDBM50306458 (6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carboxylate::CHEMBL598730

SMILES COC(=O)c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31

InChI Key InChIKey=TZMNVWQJGVVEND-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306458   

TargetD(1A) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306458((6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306458((6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,...)
Affinity DataKi:  3.70nMAssay Description:Displacement of radioligand from dopamine D5 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306458((6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,...)
Affinity DataKi:  923nMAssay Description:Displacement of [3H]methylspiperon from dopamine D2 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306458((6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,...)
Affinity DataKi:  4.83E+3nMAssay Description:Displacement of radioligand from dopamine D4 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed