BDBM50306210 2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-carboxamide::CHEMBL609862

SMILES CNCc1ccc(cc1)-n1cc2cccc(C(N)=O)c2n1

InChI Key InChIKey=BNTVUFYBGXHEDO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306210   

TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50306210(2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-ca...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50306210(2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-ca...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50306210(2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-ca...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human PARP1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed