BDBM50306101 (S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-3-yl)pyridin-3-yloxy)-3-phenylpropan-2-amine::CHEMBL604060

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1-c1ccsc1

InChI Key InChIKey=VPHOSYHDFSVNET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306101   

TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306101((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-3-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306101((S)-1-(5-(3-methyl-1H-indazol-5-yl)-6-(thiophen-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed