BDBM50306087 (S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-indazol-5-yl)pyridin-2-yl)phenol::CHEMBL595685

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1-c1ccc(O)cc1

InChI Key InChIKey=RFEGALABMKZYJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306087   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306087((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of full length AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306087((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed