BDBM50306030 3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL595937

SMILES CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)nc3c(cccn23)C(F)(F)F)c1

InChI Key InChIKey=XBWKFFVZKTYRJE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306030   

TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306030(3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306030(3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-...)
Affinity DataEC50:  2.28E+3nMAssay Description:Agonist activity at human Gal4-LBD fused LXRbeta LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306030(3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-...)
Affinity DataIC50: 561nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306030(3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-...)
Affinity DataEC50:  680nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed