BDBM50305974 (S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide::CHEMBL594671

SMILES CC(C)[C@@H](c1ccc(cc1)Cl)C(=O)Nc2nccs2

InChI Key InChIKey=AZYDQCGCBQYFSE-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305974   

TargetFree fatty acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataIC50: 700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFree fatty acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  417nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 2(Mouse)
Ogeda

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  158nMAssay Description:Agonist activity at mouse FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed