BDBM50305841 CHEMBL605201::N1,N3-bis(3-methoxybenzyl)isophthalamide

SMILES COc1cccc(CNC(=O)c2cccc(c2)C(=O)NCc2cccc(OC)c2)c1

InChI Key InChIKey=XDBOLPFDJWTESQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50305841   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(N1,N3-bis(3-methoxybenzyl)isophthalamide | CHEMBL6...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed