BDBM50305741 1,4-ditosylpiperazine::CHEMBL596080

SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=LMIXCJFVEQOWSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305741   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305741(1,4-ditosylpiperazine | CHEMBL596080)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305741(1,4-ditosylpiperazine | CHEMBL596080)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed