BDBM50305655 3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol::CHEMBL611021

SMILES Oc1cccc(c1)-c1nc(N2CCCCC2)c2[nH]cnc2n1

InChI Key InChIKey=HBKAYDPFQWXZQU-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50305655   

LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in CHO-A1 cells incubated for 60 mins by scintillation counting method based radioligand c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]NECA from human A3 receptor expressed in HeLa-A3 cells incubated for 180 mins by scintillation counting method based radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]DPCPX from human A2B receptor expressed in HEK-293-A2B cells incubated for 30 mins by scintillation counting method based radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HeLa-A2A cells incubated for 30 mins by scintillation counting method based radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed