BDBM50305639 CHEMBL592741::N-(2,4-dichlorobenzyl)-4-(3-(methylsulfonyl)phenoxy)piperidine-1-carboxamide

SMILES CS(=O)(=O)c1cccc(OC2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)c1

InChI Key InChIKey=ZEPNGNWMMYJWPW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305639   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305639(N-(2,4-dichlorobenzyl)-4-(3-(methylsulfonyl)phenox...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305639(N-(2,4-dichlorobenzyl)-4-(3-(methylsulfonyl)phenox...)
Affinity DataEC50:  0.25nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed