BDBM50305634 CHEMBL589375::N-(2,4-dichlorobenzyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine-1-carboxamide

SMILES FC(F)(F)Oc1ccc(OC2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)cc1

InChI Key InChIKey=KXSZHUYAHSPJGP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305634   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305634(N-(2,4-dichlorobenzyl)-4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: 12nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305634(N-(2,4-dichlorobenzyl)-4-(4-(trifluoromethoxy)phen...)
Affinity DataEC50:  18nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed