BDBM50305589 CHEMBL595149::N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesulfonamide

SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1

InChI Key InChIKey=VRHXEPNJEQXSSS-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50305589   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataIC50: 110nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataIC50: 330nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataEC50:  4.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of mouse liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataIC50: 330nMAssay Description:Inhibition of FBPase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed