BDBM50305585 CHEMBL589861::N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesulfonamide

SMILES Cc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1

InChI Key InChIKey=UGGXZOFPTPJQCH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305585   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305585(N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesu...)
Affinity DataIC50: 170nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305585(N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesu...)
Affinity DataIC50: 310nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305585(N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesu...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed