BDBM50305524 5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine::CHEMBL594591

SMILES COc1ccc(cn1)-n1c(C)nnc1N1CC(C1)Oc1ccc(F)cc1C

InChI Key InChIKey=YCUKNIRQPJXXQQ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50305524   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305524(5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  17.5nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305524(5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  17.5nMAssay Description:Antagonist activity at human oxytocin receptor expressed in CHO cells by beta lactamase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305524(5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  608nMAssay Description:Antagonist activity at human cloned vasopressin V1a receptor by cell based beta lactamase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305524(5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  608nMAssay Description:Antagonist activity at human vasopressin V1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305524(5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned vasopressin V2 receptor by cell based beta lactamase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed