BDBM50305369 (1S,3aR,6aR)-2-methyl-5-(6-phenylpyridazin-3-yl)-1-((pyridin-3-yloxy)methyl)octahydropyrrolo[3,4-c]pyrrole::CHEMBL589164

SMILES CN1C[C@@H]2CN(C[C@@H]2[C@H]1COc1cccnc1)c1ccc(nn1)-c1ccccc1

InChI Key InChIKey=XXFPUZNLBBEBHL-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305369   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305369((1S,3aR,6aR)-2-methyl-5-(6-phenylpyridazin-3-yl)-1...)
Affinity DataEC50:  1.29E+4nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes assessed as induction of Ca2+ currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305369((1S,3aR,6aR)-2-methyl-5-(6-phenylpyridazin-3-yl)-1...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]585539 from alpha7 nAChR in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed