BDBM50305296 5-(9-(1-(4-chlorobenzyl)piperidin-4-yl)-6-morpholino-9H-purin-2-yl)pyridin-3-ol::CHEMBL590620

SMILES Oc1cncc(c1)-c1nc(N2CCOCC2)c2ncn(C3CCN(Cc4ccc(Cl)cc4)CC3)c2n1

InChI Key InChIKey=GSFVUGVRHJRWKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305296   

LigandPNGBDBM50305296(5-(9-(1-(4-chlorobenzyl)piperidin-4-yl)-6-morpholi...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305296(5-(9-(1-(4-chlorobenzyl)piperidin-4-yl)-6-morpholi...)
Affinity DataIC50: 119nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305296(5-(9-(1-(4-chlorobenzyl)piperidin-4-yl)-6-morpholi...)
Affinity DataIC50: 160nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed