BDBM50305211 3-(2-hydroxyphenyl), 5-(4-hydroxyphenyl)-4, 5-dihydro-1H-pyrazole::CHEMBL590120

SMILES Oc1ccc(cc1)C1CC(N=N1)c1ccccc1O

InChI Key InChIKey=QFHXTJUGSNDMNU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305211   

TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50305211(3-(2-hydroxyphenyl), 5-(4-hydroxyphenyl)-4, 5-dihy...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50305211(3-(2-hydroxyphenyl), 5-(4-hydroxyphenyl)-4, 5-dihy...)
Affinity DataKi:  600nMAssay Description:Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50305211(3-(2-hydroxyphenyl), 5-(4-hydroxyphenyl)-4, 5-dihy...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed