BDBM50305093 (+/-)-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one::CHEMBL606149

SMILES Fc1ccc2[nH]cc(CCCNC3COc4ccc5CCNC(=O)c5c4C3)c2c1

InChI Key InChIKey=BGGVCPBLHFFERX-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305093   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305093((+/-)-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305093((+/-)-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,...)
Affinity DataKi:  10nMAssay Description:Displacement of labeled paroxetine from 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305093((+/-)-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed