BDBM50305087 21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine::CHEMBL594787

SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(C[C@@H](c2cccc(c2)[N+]([O-])=O)[C@]35C=C1)OC

InChI Key InChIKey=VWQZGDTVUHHSDR-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305087   

TargetMu-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataEC50:  302nMAssay Description:Agonist activity at rat mu opioid receptor assessed as stimulation of [35]SGTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat mu receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50305087(21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenot...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from rat delta receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed