BDBM50305038 (5-chloro-6-(4-chlorophenylamino)pyridin-3-yl)(3-methylpiperidin-1-yl)methanone::CHEMBL594296

SMILES CC1CCCN(C1)C(=O)c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=AKRBCPCYMFKJLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305038   

TargetMetabotropic glutamate receptor 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305038((5-chloro-6-(4-chlorophenylamino)pyridin-3-yl)(3-m...)
Affinity DataIC50: 95nMAssay Description:Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed