BDBM50304968 (S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile::CHEMBL602851

SMILES CC(C)CS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=DPXITRVBJLQXDO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304968   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304968((S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at PR in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304968((S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304968((S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304968((S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed