BDBM50304791 CHEMBL592986::N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-yl)-N-methylisobutyramide

SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(cc23)N(C)C(=O)C(C)C)cc1Cl

InChI Key InChIKey=ZDIFDTMGUHHPQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304791   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304791(N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxye...)
Affinity DataIC50: 3nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304791(N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxye...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed