BDBM50304788 CHEMBL594160::methyl 4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-yl(methyl)carbamate

SMILES COC(=O)N(C)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC

InChI Key InChIKey=HHYZCHIATOFILW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304788   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304788(methyl 4-(3-chloro-4-methoxybenzylamino)-8-(2-hydr...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304788(methyl 4-(3-chloro-4-methoxybenzylamino)-8-(2-hydr...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed