BDBM50304785 2-(4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-6-[(dimethylsulfamoyl)amino]-7-methoxyquinazolin-8-yl)ethan-1-ol::CHEMBL593225

SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NS(=O)(=O)N(C)C)cc23)cc1Cl

InChI Key InChIKey=GCBJQSZJMUMFEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304785   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304785(2-(4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-6-[...)
Affinity DataIC50: 12nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304785(2-(4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-6-[...)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed