BDBM50304783 (+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamide::(-)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamide::2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamide::CHEMBL594544

SMILES OCC(\C=C\c1ccc(F)cc1)N1CCN(CC1)c1ncc(cn1)C(=O)NO

InChI Key InChIKey=UOEXMKBLKQPTKA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50304783   

TargetHistone deacetylase 5(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 207nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 102nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 224nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed