BDBM50304782 CHEMBL609583::N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamide

SMILES ONC(=O)c1cnc(nc1)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=MUTBJZVSRNUIHA-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50304782   

TargetHistone deacetylase 5(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed