BDBM50304680 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-cyclopropylurea::CHEMBL594244

SMILES CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CC5CCC(C4)O5)c3s2)-c2ccc(NC(=O)NC3CC3)cc2)CC1

InChI Key InChIKey=NLNIZBXJXWGGBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304680   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304680(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304680(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50: 179nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed