BDBM50304661 4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-4,7-di(3-methoxy-thiophenyl)-quinoline-3-yl)-ethenyl]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one::CHEMBL608986

SMILES COc1cccc(Sc2cc3nc(C4CC4)c(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)c(Sc4cccc(OC)c4)c3cc2F)c1

InChI Key InChIKey=JILRKAQJHRATAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304661   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304661(4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-4,7-di(3-m...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed