BDBM50304659 (4R,6S)-6-((E)-2-(2-cyclopropyl-6,7-difluoro-4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one::CHEMBL595984

SMILES CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)c(nc3cc(F)c(F)cc23)C2CC2)cc1

InChI Key InChIKey=ITMHPLSBGQUZLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304659   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304659((4R,6S)-6-((E)-2-(2-cyclopropyl-6,7-difluoro-4-(4-...)
Affinity DataIC50: 7.59E+5nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed