BDBM50304657 (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-isopropylphenylthio)-6-methoxyquinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one::CHEMBL594578

SMILES COc1ccc2nc(C3CC3)c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)c(Sc3ccc(cc3)C(C)C)c2c1

InChI Key InChIKey=BZWGQJAEHJZWEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304657   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304657((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-isopropylphen...)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed