BDBM50304652 (4R,6S)-6-[(E)-2-[2-Cyclopropyl-4-(4-fluorothiophenyl)-quinoline-3-yl]-ethenyl]-3,4,5,6-tetrahydro-4-hydroxy-2Hpyran-2-one::CHEMBL595988

SMILES O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Sc2ccc(F)cc2)c2ccccc2nc1C1CC1

InChI Key InChIKey=MZZUIPBEYLQBNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304652   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304652((4R,6S)-6-[(E)-2-[2-Cyclopropyl-4-(4-fluorothiophe...)
Affinity DataIC50: 6.24E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed