BDBM50304605 5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione::5-[4-Hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione::CHEMBL595469

SMILES Oc1ccc(cc1)-c1nnc(S)s1

InChI Key InChIKey=SPCOJHSDAVLPJE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304605   

LigandPNGBDBM50304605(5-[4-Hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50304605(5-[4-Hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataKi:  190nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50304605(5-[4-Hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed