BDBM50304431 CHEMBL594821::N-{4-[4-(2-Aminoethyl)piperazin-1-yl]phenyl}-7-(3,5-difluorobenzyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

SMILES NCCN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1

InChI Key InChIKey=OSTIUWSBIRQLMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304431   

TargetSignal transducer and activator of transcription 6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304431(N-{4-[4-(2-Aminoethyl)piperazin-1-yl]phenyl}-7-(3,...)
Affinity DataIC50: 34nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed