BDBM50304367 CHEMBL595786::N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)naphthalene-2-sulfonamide::US9320734, 455

SMILES Cc1nnc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc2)s1

InChI Key InChIKey=YHFXJWRRQDJXOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304367   

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM50304367(N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304367(N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed