BDBM50304289 1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methylthiophenyl-ureido)-2H-isoquinolin-3-one::CHEMBL596265

SMILES COc1ccc(cc1)-c1n(NC(=O)Nc2ccc(SC)cc2)c(=O)cc2cc3OCOc3cc12

InChI Key InChIKey=KDCNFQOPLAMXSF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304289   

TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50304289(1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methyl...)
Affinity DataKi:  850nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50304289(1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methyl...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50304289(1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methyl...)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed