BDBM50304269 (2S,4R)-1-(4,4-diphenylbut-3-enyl)-4-hydroxypyrrolidine-2-carboxylic acid::CHEMBL594451

SMILES [#8]-[#6@@H]-1-[#6]-[#6@H](-[#7](-[#6]-[#6]\[#6]=[#6](\c2ccccc2)-c2ccccc2)-[#6]-1)-[#6](-[#8])=O

InChI Key InChIKey=GKQHRYSTFPKYKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304269   

TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Institute of Microbiology

Curated by ChEMBL
LigandPNGBDBM50304269((2S,4R)-1-(4,4-diphenylbut-3-enyl)-4-hydroxypyrrol...)
Affinity DataIC50: 7.96E+4nMAssay Description:Inhibition of GAT1 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Institute of Microbiology

Curated by ChEMBL
LigandPNGBDBM50304269((2S,4R)-1-(4,4-diphenylbut-3-enyl)-4-hydroxypyrrol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT3 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed