BDBM50304268 (S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pyrrolidin-2-yl)acetic acid::CHEMBL603863

SMILES [#6]-c1ccsc1\[#6](=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6]-[#6](-[#8])=O)-c1sccc1-[#6]

InChI Key InChIKey=ZFYBTKLTULKJOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304268   

TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Institute of Microbiology

Curated by ChEMBL
LigandPNGBDBM50304268((S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl...)
Affinity DataIC50: 340nMAssay Description:Inhibition of GAT1 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Institute of Microbiology

Curated by ChEMBL
LigandPNGBDBM50304268((S)-2-(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of GAT3 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed