BDBM50304178 CHEMBL4164713

SMILES OC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=QDHAZAAJSGGQDF-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304178   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304178(CHEMBL4164713)
Affinity DataKd:  480nMAssay Description:Binding affinity to MCL1 (unknown origin) assessed as inhibition of Mcl1-FAMbid protein-protein interaction after 1 min by fluorescence polarization ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304178(CHEMBL4164713)
Affinity DataKi:  480nMAssay Description:Displacement of FAM labelled Bid-derived peptide from MCL1 (unknown origin) incubated for 1 min by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50304178(CHEMBL4164713)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of FAM labelled Bid-derived peptide from Bcl-2 (unknown origin) incubated for 1 min by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed