BDBM50304122 (Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL604470

SMILES [O-][N+](=O)c1cc2C(C(=O)Nc2c(Br)c1)c1[nH]c2ccc(Br)cc2c1N=O

InChI Key InChIKey=SSCMCPNEHSIBSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304122   

LigandPNGBDBM50304122((Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304122((Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed