BDBM50304121 (Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL507274

SMILES [O-][N+](=O)c1ccc2NC(=O)C(c2c1)c1[nH]c2ccc(Br)cc2c1N=O

InChI Key InChIKey=VBOZZVDANBDMIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304121   

LigandPNGBDBM50304121((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304121((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50304121((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed