BDBM50303998 2-Benzyl-4-piperazin-1-yl-1H-benzimidazole::CHEMBL578411

SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccccc1

InChI Key InChIKey=YTVICZASURPPDE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303998   

Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303998(2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of serotonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303998(2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303998(2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed