BDBM50303938 4-methoxynaphthalen-1-amine::CHEMBL572058

SMILES COc1ccc(N)c2ccccc12

InChI Key InChIKey=JVMUPDOMGALPOW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303938   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303938(4-methoxynaphthalen-1-amine | CHEMBL572058)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303938(4-methoxynaphthalen-1-amine | CHEMBL572058)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303938(4-methoxynaphthalen-1-amine | CHEMBL572058)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of KAT3B catalytic domain (1284 to 1673 residues) (unknown origin) using SGRGKGGKGLGKGGAKRHRK-NH2 as substrate after 5 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303938(4-methoxynaphthalen-1-amine | CHEMBL572058)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of KAT2B catalytic domain (492 to 658 residues) (unknown origin) using H-ARTKQTARKSTGGKAPRKQL-OH as substrate after 5 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed