BDBM50303754 2-Imino-5,5-diphenyl-imidazolidin-4-one::2-amino-4,4-diphenyl-1H-imidazol-5(4H)-one::CHEMBL56002

SMILES NC1=NC(C(=O)N1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=KMAGLUVYQQBXIR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303754   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303754(2-amino-4,4-diphenyl-1H-imidazol-5(4H)-one | 2-Imi...)
Affinity DataEC50:  2.35E+4nMAssay Description:Inhibition of BACE1 expressed in CHOK1 cells coexpressing human recombinant wild type APP assessed as blockade of amyloid beta production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303754(2-amino-4,4-diphenyl-1H-imidazol-5(4H)-one | 2-Imi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303754(2-amino-4,4-diphenyl-1H-imidazol-5(4H)-one | 2-Imi...)
Affinity DataIC50: 8.72E+4nMAssay Description:Inhibition of human BACE2 by FRET based peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed