BDBM50303690 CHEMBL566015::Thiophene-2-sulfonic Acid[(E)-3-(1-Benzo[1,3]dioxol-5-ylmethyl-1H-indol-7-yl)acryloyl]amide

SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4OCOc4c3)c12

InChI Key InChIKey=DKRMVIMIBYWMCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303690   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303690(Thiophene-2-sulfonic Acid[(E)-3-(1-Benzo[1,3]dioxo...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303690(Thiophene-2-sulfonic Acid[(E)-3-(1-Benzo[1,3]dioxo...)
Affinity DataIC50: 2.21E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed