BDBM50303669 CHEMBL567266::Naphthalene-2-carboxylic acid{4-[(E)-3-(4,5-dichloro-thiophene-2-sulfonylamino)-3-oxopropenyl]-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl}-amide

SMILES CN1C(=O)C(NC(=O)c2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1

InChI Key InChIKey=LEOYZGDFRWUAOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303669   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303669(Naphthalene-2-carboxylic acid{4-[(E)-3-(4,5-dichlo...)
Affinity DataIC50: 14.6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303669(Naphthalene-2-carboxylic acid{4-[(E)-3-(4,5-dichlo...)
Affinity DataIC50: 2.25E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed