BDBM50303400 CHEMBL577546::S-2-(3-chlorophenylamino)-2-oxoethyl carbamothioate

SMILES NC(=O)SCC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=IHUXDOWGVBEMAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303400   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303400(S-2-(3-chlorophenylamino)-2-oxoethyl carbamothioat...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by quantitative high throughput screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303400(S-2-(3-chlorophenylamino)-2-oxoethyl carbamothioat...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by Flexstation microplate spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50303400(S-2-(3-chlorophenylamino)-2-oxoethyl carbamothioat...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PA14 LasB elastase preincubated for 15 mins followed by substrate addition and measured after 60 mins using 2-am...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed