BDBM50303237 ((1S,3'R,4'S,5'S,6'R)-5-chloro-3',4',5'-trihydroxy-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-4-yl)(4-ethylphenyl)methanone::CHEMBL567058

SMILES CCc1ccc(cc1)C(=O)c1c2CO[C@]3(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2ccc1Cl

InChI Key InChIKey=XJXAHMPHRVZWNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303237   

TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303237(((1S,3'R,4'S,5'S,6'R)-5-chloro-3',4',5'-trihydroxy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50303237(((1S,3'R,4'S,5'S,6'R)-5-chloro-3',4',5'-trihydroxy...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed